162780-03-2

Upstream product

• 39110-21-9 [(4-methylphenyl)methylene]triphenylphosphorane 
• 162779-96-6 (3R,4S)-1-Benzyl-3-hydroxy-4-(2-p-tolyl-ethyl)-azetidin-2-one 
• 150949-66-9 (+)-(3R,4R)-cis-1-benzyl-3-benzyloxy-4-formyl-2-azetidinone 

Downstream Products

• 162780-10-1 (S)-3-Benzyl-4-(2-p-tolyl-ethyl)-oxazolidine-2,5-dione 

Relevant academic research and scientific papers

A β-Lactam Framework as a β-Alanyl Dication Equivalent: New Synthesis of α-Amino Acid N-carboxy Anhydrides (NCAs) Derived from β-Substituted Alanines

Optically pure 4-formyl-3-hydroxy β-lactams are transformed into 4-methylaryl and 4-(2-ethylaryl) derivatives and converted into β-substituted alanine-derived NCAs through oxidation and Baeyer-Villiger rearrangement of the resulting α-keto β-lactams.