162780-20-3Relevant academic research and scientific papers
A β-Lactam Framework as a β-Alanyl Dication Equivalent: New Synthesis of α-Amino Acid N-carboxy Anhydrides (NCAs) Derived from β-Substituted Alanines
Palomo, Claudio,Aizpurua, Jesus M.,Ganboa, Inaki,Maneiro, Elena,Odriozola, Beatriz
, p. 1505 - 1508 (2007/10/02)
Optically pure 4-formyl-3-hydroxy β-lactams are transformed into 4-methylaryl and 4-(2-ethylaryl) derivatives and converted into β-substituted alanine-derived NCAs through oxidation and Baeyer-Villiger rearrangement of the resulting α-keto β-lactams.
