1628191-50-3Relevant articles and documents
Copper-Mediated Synthesis of Aryl α-Keto Amides from Epoxide Derivatives
Cui, Yunjian,Dong, Yi,Liu, Fenghua,Xu, Heng
supporting information, p. 1011 - 1014 (2020/06/10)
A novel Cu II -mediated synthesis of aryl α-keto amides from epoxide derivatives is reported. This transformation was conducted by using O 2 as a green oxidant that meets the requirements of sustainable chemistry.
Copper-catalyzed, hypervalent iodine mediated C=C bond activation of enaminones for the synthesis of α-keto amides
Wan, Jie-Ping,Lin, Yunfang,Cao, Xiaoji,Liu, Yunyun,Wei, Li
supporting information, p. 1270 - 1273 (2016/01/15)
An unprecedented C=C bond cleavage of enaminones has been realized by means of copper catalysis in the presence of hypervalent iodine (PhI(OAc)2). The cascade transformation based on this bond cleavage leads to the synthesis of various α-keto amides. Isotope labeling experiments suggest that water has acted as a source of oxygen atoms during the generation of the new carbonyl group.