1628258-95-6

Basic information

• Product Name: cis-tert-butyl 3-aMino-2-Methylpiperidine-1-carboxylate
• Synonyms: cis-tert-butyl 3-aMino-2-Methylpiperidine-1-carboxylate;tert-butyl (2R,3R)-3-amino-2-methylpiperidine-1-carboxylate
• CAS NO: 1628258-95-6
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.30458
• Mol File: 1628258-95-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cis-tert-butyl 3-aMino-2-Methylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: cis-tert-butyl 3-aMino-2-Methylpiperidine-1-carboxylate(1628258-95-6)
• EPA Substance Registry System: cis-tert-butyl 3-aMino-2-Methylpiperidine-1-carboxylate(1628258-95-6)

Safety Data

• Hazardous Substances Data: 1628258-95-6(Hazardous Substances Data)

Upstream product

• 828300-51-2 trans-(±)-1-(tert-butoxycarbonyl)-2-methylpiperidine-3-carboxylic acid 
• 65719-09-7 methyl 2-methylnicotinate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 828300-51-2 (2R*,3R*)-1-[(tert-butoxy)carbonyl]-2-methylpiperidine-3-carboxylic acid 

Relevant articles and documents

SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS

The present invention is directed to compounds of Formula I: wherein X is CR1 or N; Y is CR2 or N; Z is NH or O; R1 is alkoxy, triazolyl, oxazolyl, isoxazolyl, oxadiazolyl, or pyrimidinyl; R2 is H, alkyl, or halo; R3 is H, alkyl, alkoxy, halo, triazolyl, oxazolyl, or pyrimidinyl; R4 is alkyl; R5 is pyridyl; benzoxazolyl; pyrimidinyl; pyridazinyl; quinoxalinyl; pyrazinyl; or quinazolinyl; wherein the pyridyl; benzoxazolyl; pyrimidinyl; pyridazinyl; quinoxalinyl; pyrazinyl; or quinazolinyl is optionally substituted with one or two substituents independently selected from the group consisting of alkyl, halo, or phenyl; and R6 is H or alkyl. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula I. Methods of using the compounds of the invention are also within the scope of the invention.