1628342-32-4Relevant academic research and scientific papers
New substituted pyrroles obtained in searching for pyrrolo[1,2-a] quinazoline framework
Dumitrescu, Denisa,Popa, Marcel Mirel,Georgescu, Florentina,Georgescu, Emilian,Barbub, Loredana,Dumitrascu, Florea
, p. 785 - 790 (2014/06/24)
The synthesis of new highly substituted N-arylpyrroles was achieved by 1,3-dipolar cycloaddition of the quinazolinium N-ylides with acetylenic dipolarophiles. The reaction was conducted as one-pot procedure in 1,2-epoxybutane as reaction medium and proton scavenger. Structural variety of compounds was conferred by the use of various symmetrical and non-symmetrical acetylenic dipolarophiles. In the case of symmetrical dipolarophiles (i.e. Dimethyl acetylenedicarboxylate) the pyr-rolo[1,2-a]quinazoline framework could be isolated and characterized.
