1628430-28-3 Usage
Molecular weight
476.5
Chemical structure
1-Piperidinecarboxylic acid, 4-(2,3-difluorophenyl)-4-hydroxy-, 1,1-dimethylethyl ester
Mechanism of action
Stabilizes the transthyretin protein
Route of administration
Oral
Indications
Treatment of transthyretin amyloidosis (ATTR)
Effect
Slows down the progression of ATTR and improves symptoms
Target protein
Transthyretin
Function of target protein
Transports thyroid hormone and vitamin A in the blood
Disease caused by malfunction of target protein
ATTR
Characterization of disease
Rare and progressive condition characterized by build-up of abnormal proteins in various tissues and organs, leading to damage and dysfunction.
Check Digit Verification of cas no
The CAS Registry Mumber 1628430-28-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,8,4,3 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1628430-28:
(9*1)+(8*6)+(7*2)+(6*8)+(5*4)+(4*3)+(3*0)+(2*2)+(1*8)=163
163 % 10 = 3
So 1628430-28-3 is a valid CAS Registry Number.