162854-37-7

Basic information

• Product Name: Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetrahydroxy-
• Synonyms: 2,3,9,10-Tetrahydroxyberberine; 2,3-Desmethylene-9,10-desmethylberberine; 9,10-Di-O-demethyl-2,3-O-demethyleneberberine
• CAS NO: 162854-37-7
• Molecular Formula: C₁₇H₁₄NO₄
• Molecular Weight: 296.30
• Mol File: 162854-37-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetrahydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetrahydroxy-(162854-37-7)
• EPA Substance Registry System: Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetrahydroxy-(162854-37-7)

Safety Data

• Hazard Codes: A poison

Upstream product

• 633-65-8 berberine chloride 
• 2086-83-1 berberine 

Downstream Products

• 3486-67-7 palmatine 

Relevant articles and documents

Gastric-mucous membrane protection activity of coptisine derivatives

Coptisine and 8-oxocoptisine were isolated as principles of the gastric-mucous membrane protection from Coptidis rhizoma. The two compounds showed stronger activity than cimetidine and sucralfate. We prepared several derivatives having a partial structure of coptisine from commercially available starting materials. The compounds obtained were tested for gastric-mucous membrane protective activity and a correlation between activity and structure was studied. Our results suggest that the partial charge of the catechol skeleton is related to activity.