1628563-56-3Relevant academic research and scientific papers
Synthesis of Fused Dihydroazepine Derivatives of Fullerenes by a Rh-Catalyzed Cascade Process
Artigas, Albert,Castanyer, Cristina,Lledó, Agustí,Pla-Quintana, Anna,Roglans, Anna,Roig, Nil,Solà, Miquel
, p. 3835 - 3844 (2021)
A synthetic methodology is reported that functionalizes C60 and C70 fullerenes with dihydroazepine rings by a cascade reaction encompassing a rhodium-catalyzed cycloisomerization of 1,5-bisallenes and a [4+2] cycloaddition. This tran
A Rh(I)-Catalyzed Cascade Cyclization of 1,5-Bisallenes and Alkynes for the Formation of cis-3,4-Arylvinyl Pyrrolidines and Cyclopentanes
Vila, Jordi,Vinardell, Roger,Solà, Miquel,Pla-Quintana, Anna,Roglans, Anna
supporting information, p. 206 - 217 (2021/11/17)
The cascade cyclization reactions of 1,5-bisallenes grant access to a great variety of products by precisely tuning the catalyst system and/or the reagents involved. Herein, we present our findings that 1,5-bisallenes react with two molecules of dimethyl acetylenedicarboxylate to afford, in a completely diastereoselective manner, cis-3,4-arylvinyl pyrrolidines and cyclopentanes. DFT calculations have been used to postulate a mechanism for the developed reaction which encompasses a [2+2+2] cycloaddition reaction of the two alkynes and the external double bond of one allene, followed by a cycloisomerization involving the internal double bond of the second allene. (Figure presented.).
Asymmetric, organocatalytic bromolactonization of allenoic acids
Wilking, Michael,Daniliuc, Constantin G.,Hennecke, Ulrich
supporting information, p. 1701 - 1704 (2014/08/05)
Asymmetric, reagent-controlled bromolactonizations of allenoic acids have been achieved by using (DHQD)2PHAL as catalyst. A range of substrates can be cyclized in good yields and moderate to good enantioselectivities under operationally simple conditions. Georg Thieme Verlag Stuttgart New York.
