1628813-19-3Relevant academic research and scientific papers
2,6-difunctionalization of N-substituted dithienothiazines via dilithiation
Dostert, Catherine,Czajkowski, Daniel,Müller, Thomas J. J.
supporting information, p. 371 - 374 (2014/03/21)
The regioselective lithiation of dithienothiazines followed by electrophilic trapping in a one-pot fashion is an efficient route to 2-mono- and 2,6-difunctionalized dithienothiazines. A pseudo five-component dilithiation-diformylation-double-Wittig olefination sequence gives a dithienothiazine symmetrically functionalized with α,β-unsaturated ester side chains in excellent yield. Georg Thieme Verlag Stuttgart. New York.
