1629124-86-2

Upstream product

• 1026073-72-2 [(1R,2R,3S)-1-hydroxy-3-methylcyclohex-2-yl] 2,3,4-tri-O-benzyl-6-deoxy-α-L-galactopyranoside 
• 1629124-85-1 C₅₀H₅₆N₂O₉S 

Downstream Products

• 1629124-87-3 C₂₇H₄₈N₂O₁₃ 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS TO ENHANCE THE ORAL AVAILABILITY OF GLYCOMIMETICS

Compounds and methods are provided for enhancing the oral availability of glycomimetics. More specifically, in an embodiment, a glycomimetic is modified to decrease the polar surface area of the glycomimetic in order to increase absorption from the GI tract. In another embodiment, a glycomimetic is targeted to an active transport system, such as the bile acid active transport system, that provides transport across a biological membrane in order to increase absorption of the glycomimetic from the Gl tract.

COMPOUNDS AND METHODS TO ENHANCE THE ORAL AVAILABILITY OF GLYCOMIMETICS

Potent E-selecting antagonist compounds are described herein. In certain embodiments, compounds and methods are provided for enhancing the oral availability of glycomimetics. More specifically, in an embodiment, a glyeomimetic is modified to decrease the