1629670-53-6Relevant academic research and scientific papers
Azo-sulforhodamine dyes: A novel class of broad spectrum dark quenchers
Chevalier, Arnaud,Renard, Pierre-Yves,Romieu, Anthony
, p. 3946 - 3949 (2014)
A rapid access to a novel class of water-soluble dark quencher dyes was achieved using an azo-coupling reaction between a fluorescent primary arylamine derived from a sulforhodamine 101 scaffold and a tertiary aniline equipped with different bioconjugatable groups. The thus obtained nonfluorescent azo-sulforhodamine hybrids display a broad quenching range spanning the visible to NIR regions. This was demonstrated through the preparation and enzymatic activation of FRET-based fluorogenic substrates of urokinase.
Straightforward access to water-soluble unsymmetrical sulfoxanthene dyes: Application to the preparation of far-red fluorescent dyes with large stokes' shifts
Chevalier, Arnaud,Renard, Pierre-Yves,Romieu, Anthony
supporting information, p. 8330 - 8337 (2014/07/08)
An efficient synthesis of water-soluble unsymmetrical sulforhodamine/ sulforhodol fluorophores containing a single julolidine fragment is presented. Owing to their valuable spectral properties in aqueous buffers, these dyes, especially those bearing a free aniline or phenol moiety, are valuable components of fluorogenic probes for a variety of biosensing applications. A further extension of this synthetic methodology to unusual phenols, namely 7-N,N-dialkylamino-4-hydroxy coumarins has enabled us to provide a new family water-soluble dyes of large Stokes' shift with far-red spectral features.
