1630041-13-2Relevant academic research and scientific papers
Exploration of uracils: Pot and step economic production of pyridine core containing templates by multicomponent aza-Diels-Alder reaction
Sarmah, Manas M.,Prajapati, Dipak
, p. 22955 - 22958 (2014/06/24)
An efficient pot and step economic protocol for synthesis of pyrido[2,3-d]pyrimidine derivatives from a multicomponent aza-Diels-Alder reaction of uracil analogues, aromatic aldehydes and acetophenones in the presence of Na2CO3 in DMF was developed. The key step of the reaction is in situ generation of the reactive dienophile from aldehyde and acetophenone and their subsequent reaction with diene to give the desired product.
