163018-26-6

Basic information

• Product Name: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether
• Synonyms: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether;(3β,5Z,7E)-3-(3-AMinopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol;(εR,1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-(3-AMinopropoxy)-2-Methylenecyclohexylidene]ethylidene]octahydro-α,α,ε,7a-tetraMethyl-1H-indene-1-pentanol;3-O-(2-AMinoethyl)-25-hydroxyvitaMin D3;3-O-(2-Aminopropyl)-25-hydroxyvitamin D3;25-Hydroxy Vitamin D3 3
• CAS NO: 163018-26-6
• Molecular Formula: C₃₀H₅₁NO₂
• Molecular Weight: 457.73144
• Product Categories: Amines;Chiral Reagents;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 163018-26-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 580.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.00±0.1 g/cm3(Predicted)
• Storage Temp.: Amber Vial, -20?C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 15.32±0.29(Predicted)
• Stability: Light Sensitive, Temperature Sensitive
• CAS DataBase Reference: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether(CAS DataBase Reference)
• NIST Chemistry Reference: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether(163018-26-6)
• EPA Substance Registry System: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether(163018-26-6)

Safety Data

• Hazardous Substances Data: 163018-26-6(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Low-Melting Solid

Uses

Vitamin D3 analog.

Upstream product

• 133191-10-3 3-(((S,Z)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)propanenitrile 

Relevant articles and documents

RNAi VITAMIN D CONJUGATES

The invention provides non-hormonal vitamin D conjugated to therapeutic RNA compounds that result in the compounds having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups

THERAPEUTIC VITAMIN D CONJUGATES

The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are couple