16307-27-0

Upstream product

• 182689-77-6 2-(4-fluorobenzylidene)-2,3-dihydroinden-1-one 
• 459-56-3 4-fluorobenzylic alcohol 
• 95-13-6 1-indene 
• 615-13-4 2-indanone 
• 1643-73-8 (4-fluorobenzyl)magnesium chloride 
• 16274-91-2 2-<4-Fluor-benzyl>-indan-2-ol 

Downstream Products

• 14669-32-0 {2-[2-(4-Fluoro-benzyl)-3H-inden-1-yl]-ethyl}-dimethyl-amine 
• 60231-39-2 2-(4-Fluoro-benzyl)-indan 

Relevant academic research and scientific papers

2-Benzylindane radical cations in the gas phase (Part I): Substituent effects on a stereoselective McLafferty reaction and related hydrogen transfer processes

In the present and the accompanying article, the unimolecular fragmentation of the radical cations of 2-benzylindane and eleven derivatives bearing meta- or para-substituents at the benzylic moiety has been studied with a special focus on the hydrogen exc

Selective catalytic C-H alkylation of alkenes with alcohols

Alkenes and alcohols are among the most abundant and commonly used organic feedstock in industrial processes. We report a selective catalytic alkylation reaction of alkenes with alcohols that forms a carbon-carbon bond between vinyl carbon-hydrogen (C-H) and carbon-hydroxy centers with the concomitant loss of water. The cationic ruthenium complex [(C6H6)(PCy 3)(CO)RuH]+BF4- (Cy, cyclohexyl) catalyzes the alkylation in solution within 2 to 8 hours at temperatures ranging from 75° to 110°C and tolerates a broad range of substrate functionality, including amines and carbonyls. Preliminary mechanistic studies are inconsistent with Friedel-Crafts-type electrophilic activation of the alcohols, suggesting instead a vinyl C-H activation pathway with opposite electronic polarization.