16307-46-3

Basic information

• Product Name: N′,N′-bis(cyclopropylmethyl)benzohydrazide
• Synonyms: N′,N′-bis(cyclopropylmethyl)benzohydrazide
• CAS NO: 16307-46-3
• Molecular Weight: 244.337
• Mol File: 16307-46-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N′,N′-bis(cyclopropylmethyl)benzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N′,N′-bis(cyclopropylmethyl)benzohydrazide(16307-46-3)
• EPA Substance Registry System: N′,N′-bis(cyclopropylmethyl)benzohydrazide(16307-46-3)

Safety Data

• Hazardous Substances Data: 16307-46-3(Hazardous Substances Data)

Upstream product

• 2516-33-8 Cyclopropylmethanol 
• 613-94-5 benzoic acid hydrazide 
• 905101-11-3 Cyclopropan-carbaldehyd-benzhydrazon 

Relevant articles and documents

Phosphine-free ruthenium complex-catalyzed synthesis of mono- Or dialkylated acyl hydrazides via the borrowing hydrogen strategy

Herein, we report a diaminocyclopentadienone ruthenium tricarbonyl complex-catalyzed synthesis of mono- or dialkylated acyl hydrazide compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary alcohols as alkylating reagents. Deuterium labeling experiments confirm that the alcohols were the hydride source in this cascade process. Density functional theory (DFT) calculations unveil the origin and the threshold between the mono- and dialkylation.