163079-25-2 Usage
General Description
2-(tert-Butyldimethylsilyl)thiophene is a chemical compound of the thiophene family characterized by the presence of a tert-Butyldimethylsilyl group. Thiophenes are essentially five-membered aromatic rings containing four carbon atoms and a sulfur atom. The tert-Butyldimethylsilyl group increases the compound's stability and reactivity in various chemical reactions. Known for its versatility, this compound is primarily used in various chemical synthesis processes and pharmaceutical manufacturing, due to its ability to form complex molecular structures. Its precise physical-chemical properties may vary, they typically include high boiling points and hydrophobicity. It must be handled with caution because of its potentially hazardous characteristics. Detailed safety protocols and handling procedures should be followed at all times to avoid harmful exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 163079-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,0,7 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 163079-25:
(8*1)+(7*6)+(6*3)+(5*0)+(4*7)+(3*9)+(2*2)+(1*5)=132
132 % 10 = 2
So 163079-25-2 is a valid CAS Registry Number.
163079-25-2Relevant articles and documents
Synthetic Applications of Arenetricarbonylchromium(0) Complexes: the Synthesis of Polyfunctionalised Thiophenes
Loft, Michael S.,Mowlem, Timothy J.,Widdowson, David A.
, p. 97 - 104 (2007/10/02)
Lithiation of thiophenetricarbonylchromium(0) complexes with butyllithium occurs preferentially at C-2/5 but when these are blocked, 3/4 lithiation is facile.Combinations of a bulky silyl (i-Pr3Si or t-BuMe2Si) blocking group at C-2/5 and remote lithiation/electrophilic quench of C-3/4 followed by desilylation/lithiation/electrophilic quench allowed the synthesis of 2,3-, 2,3,5- and 2,3,4,5-polysubstituted thiophene complexes and their derived free thiophenes.
