163083-65-6 Usage
Uses
Used in Pharmaceutical Research:
1H-Indole-3-carboxylic acid, 6-Methyl-, Methyl ester is used as a building block for the development of new pharmaceutical compounds due to its potential biological activities. Its anti-inflammatory, anti-cancer, and anti-microbial properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Indole-3-carboxylic acid, 6-Methyl-, Methyl ester serves as a key intermediate for the synthesis of various organic compounds. Its unique structure and reactivity allow it to be incorporated into a wide range of chemical reactions, facilitating the production of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 163083-65-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,0,8 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 163083-65:
(8*1)+(7*6)+(6*3)+(5*0)+(4*8)+(3*3)+(2*6)+(1*5)=126
126 % 10 = 6
So 163083-65-6 is a valid CAS Registry Number.
163083-65-6Relevant academic research and scientific papers
A general and scalable synthesis of polysubstituted indoles
Diana-Rivero, Raquel,García-Tellado, Fernando,Tejedor, David
, (2021/06/14)
A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported. The protocol is based on the [3,3]-sigmatropic rearrangement of N-oxyenamines generated by the DABCO-catalyzed reaction of N-arylhydroxylamines and conjugated terminal alkynes, and delivers indoles endowed with a wide array of substitution patterns and topologies.
A New Method for the Synthesis of 3-Substituted Indoles
Natarajan, Rakesh,Rappai, John P.,Unnikrishnan, Peruparampil A.,Radhamani, Sandhya,Prathapan, Sreedharan
supporting information, p. 2467 - 2471 (2015/10/19)
Starting from readily accessible nitrones and electron-deficient acetylenes, a highly efficient and versatile synthetic protocol for 3-substituted indoles has been developed.
