163085-40-3Relevant academic research and scientific papers
SYNTHESIS OF CERTAIN DIPYRIDYLACETYLENES USING PALLADIUM-CATALYZED CROSS-COUPLING OF ETHYNYL- AND HALOPYRIDINES
Karchava, A. V.,Maksimova, F. V.,Yurovskaya, M. A.
, p. 1195 - 1199 (1994)
A series of dipyridylacetylenes were obtained by reacting ethynylpyridines with chloro- and bromopyridines during catalysis with phosphino complexes of palladium in the presence of copper iodide and a base.
Benzamide compounds as apo b secretion inhibitors
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, (2008/06/13)
The present invention relates to compounds of the formula (I) wherein R1 and R2 are each independently lower alkyl lower alkenyl, acyl, amino, lower alkoxy, lower cycloalkyloxy, aryl, aryloxy, sulfooxy, mercapto, sulfo, hydrogen, halogen, nitro, cyano or hydroxy, or may form a ring structure; Q1 is N or CH; L is optionally substituted unsaturated 3 to 10-membered heterocyclic group; X is optionally substituted monocyclic arylene or monocyclic heteroarylene; Y is -(A1)m-(A2)n-(A4)k-; Z is directbond, —CH2-, —NH— or —O—; and R is hydrogen or lower alkyl, or a salt thereof The compounds of the present invention inhibit apolipoprotein B (Apo B) secretion and are useful as a medicament for prophylactic and treatment of diseases or conditions resulting from elevated circulating levels of Apo B.
