16309-18-5

Basic information

• Product Name: decyl 2-hydroxybenzoate
• CAS NO: 16309-18-5
• Molecular Formula: C₁₇H₂₆O₃
• Molecular Weight: 278.3865
• Mol File: 16309-18-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 367.4°C at 760 mmHg
• Flash Point: 141°C
• Density: 1.014g/cm³
• Vapor Pressure: 6.46E-06mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: decyl 2-hydroxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: decyl 2-hydroxybenzoate(16309-18-5)
• EPA Substance Registry System: decyl 2-hydroxybenzoate(16309-18-5)

Safety Data

• Hazardous Substances Data: 16309-18-5(Hazardous Substances Data)

Upstream product

• 112-30-1 1-Decanol 
• 69-72-7 salicylic acid 

Relevant articles and documents

Synthesis, computational evaluation and pharmacological assessment of acetylsalicylic esters as anti-inflammatory agents

A convenient approach to the synthesis of alkyl esters of aspirin (ASA-OR) has been developed. The synthesis of ASA-OR has been realized in two steps: (1) direct esterification of salicylic acid with alcohols in the presence of dicyclohexylcarbodiimide to give alkyl salicylates (SAL-OR); (2) acetylation of SAL-OR with acetyl chloride to yield ASA-OR. Molecular mechanics simulations, performed to calculate the kinetic radii of several ASA-OR, indicated that the pentyl and hexyl acetylsalicylates possess the best properties to cross cell membranes. The in vitro biological tests demonstrate their anti-inflammatory activity, superimposable to that of aspirin. The results of our study suggest that ASA-OR may be used as anti-inflammatory drugs for topical application.