1630906-91-0 Usage
Uses
Used in Pharmaceutical Research and Development:
1,1-Difluoro-5-azaspiro[2.3]hexane hydrochloride is used as a research compound for its potential pharmacological effects, particularly in the treatment of central nervous system disorders. Its unique spirocyclic structure and fluorine substitution may contribute to its biological activity and selectivity, making it a promising candidate for drug development.
Used in Medicinal Chemistry Research:
1,1-Difluoro-5-azaspiro[2.3]hexane hydrochloride is used as a key intermediate in the synthesis of various pharmaceutical agents. Its unique structural features and potential pharmacological properties make it an attractive building block for the development of novel therapeutic agents targeting central nervous system disorders.
Used in Drug Delivery Systems:
The hydrochloride salt form of 1,1-Difluoro-5-azaspiro[2.3]hexane hydrochloride, due to its enhanced solubility in water, can be used in the development of drug delivery systems. This improved solubility may facilitate the formulation of the compound into various dosage forms, such as tablets, capsules, or injectable solutions, enhancing its bioavailability and therapeutic efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 1630906-91-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,0,9,0 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1630906-91:
(9*1)+(8*6)+(7*3)+(6*0)+(5*9)+(4*0)+(3*6)+(2*9)+(1*1)=160
160 % 10 = 0
So 1630906-91-0 is a valid CAS Registry Number.
1630906-91-0Relevant academic research and scientific papers
Gram-Scale Synthesis of Amines Bearing a gem-Difluorocyclopropane Moiety
Nosik, Pavel S.,Gerasov, Andrii O.,Boiko, Rodion O.,Rusanov, Eduard,Ryabukhin, Sergey V.,Grygorenko, Oleksandr O.,Volochnyuk, Dmitriy M.
, p. 3126 - 3136 (2017/09/25)
The synthesis of monocyclic, spirocyclic and fused bicyclic secondary amines bearing a gem-difluorocyclopropane moiety via difluorocyclopropanation of unsaturated N-Boc derivatives using the trifluoromethyl(trimethyl)silane/sodium iodide [CF3SiMe3-NaI] system is described. The relative order of the substrate reactivity is established. It is shown that for the reactive alkenes the standard reaction conditions can be used, whereas for the substrates with low reactivity, slow addition of the Ruppert–Prakash reagent is necessary. (Figure presented.).
