163105-90-6

Basic information

• Product Name: 2-Methoxypyridine-3-boronic acid
• Synonyms: 2-Methoxypyridine-3-boronic acid ,98%;Methoxypyridinylboronicacid;2-Methoxypyridine-3;2-Methoxypyridine-3-boronic Acid (contains varying aMounts of Anhydride);3-Borono-2-methoxypyridine;Methoxy-3-pyridineboronic;2-Methoxypyridin-3-yl-3-boronic acid;2-METHOXY-3-PYRIDINYL BORONIC ACID
• CAS NO: 163105-90-6
• Molecular Formula: C₆H₈BNO₃
• Molecular Weight: 170.96
• EINECS: -0
• Product Categories: Boronic Acids & Esters;Pyridines;Heterocyclic Compounds;Organoborons;Alkoxy;Boronic Acids & Esters;Boronic Acid;Boronic Acids;Boronic Acids and Derivatives;Heteroaryl;Boronate Ester;Potassium Trifluoroborate;Pyridine;Boron, Nitrile, Thio,& TM-Cpds;Heterocycles
• Mol File: 163105-90-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 136-138°C
• Boiling Point: 326.4 °C at 760 mmHg
• Flash Point: 151.2 °C
• Appearance: White/Crystalline Powder
• Density: 1.24 g/cm³
• Vapor Pressure: 8.78E-05mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 6.90±0.58(Predicted)
• CAS DataBase Reference: 2-Methoxypyridine-3-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxypyridine-3-boronic acid(163105-90-6)
• EPA Substance Registry System: 2-Methoxypyridine-3-boronic acid(163105-90-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 163105-90-6(Hazardous Substances Data)

Usage

Chemical Properties

White to light brown powder

General Description

May contain varying amounts of anhydride.

InChI:InChI=1/C6H8BNO3/c1-11-6-5(7(9)10)3-2-4-8-6/h2-4,9-10H,1H3

Upstream product

• 1628-89-3 2-methoxypyridine 
• 112197-15-6 3-iodo-2-methoxypyridine 
• 13472-59-8 3-Bromo-2-methoxypyridine 
• 121-43-7 Trimethyl borate 

Downstream Products

• 835876-06-7 2'-methoxy-[2,3']bipyridinyl-3-ylamine 
• 918898-24-5 1-benzyl-3-indol-1-yl-4-(2-methoxy-pyridin-3-yl)-pyrrole-2,5-dione 
• 918898-25-6 1-benzyl-3-indol-1-yl-4-(2-oxo-1,2-dihydro-pyridin-3-yl)-pyrrole-2,5-dione 
• 918898-26-7 trifluoro-methanesulfonic acid 3-(1-benzyl-4-indol-1-yl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-pyridin-2-yl ester 
• 870563-36-3 N-(4-fluoro-2-(2-methoxypyridin-3-yl)benzyl)-3-(benzyloxy)-9,9-dimethyl-4-oxo-4,6,7,9-tetrahydropyrimido[2,1-c][1,4]oxazine-2-carboxamide 
• 885032-16-6 benzyl 2-methoxy-3',6'-dihydro-3,4'-bipyridine-1'(2'H)-carboxylate 
• 943152-60-1 (R)-{1-[4-(2-methoxy-pyridin-3-yl)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 943152-86-1 (R)-2-{1-[4-(2-methoxy-pyridin-3-yl)-phenyl]-ethyl}-isoindole-1,3-dione 
• 943153-38-6 (R)-(1-[3-benzyloxy-4-(2-methoxy-pyridin-3-yl)-phenyl]-ethyl)-carbamic acid tert-butyl ester 
• 881312-54-5 N-{3-cyano-6-fluoro-2-[4-(2-methoxypyridin-3-yl)phenyl]quinolin-4-yl}-D-alanine 
• 936939-51-4 2-hydroxy-5-(2-methoxy-pyridin-3-yl)-benzaldehyde 
• 936939-49-0 2-amino-4-(2-methoxypyridin-3-yl)phenylamine 
• 1029806-13-0 6,7-dimethoxy-1-[4-(2-methoxypyridin-3-yl)benzyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 1126422-74-9 5-benzyloxy-3-(2-methoxy-pyridin-3-yl)-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS

The present invention provides a compound of Formula (I): (I) or an enantiomer, an enantiomeric mixture, or a pharmaceutically acceptable salt thereof; wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating a disease or condition mediated by nuclear SET domain-containing protein 2 (NSD2).

Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin

The present invention relates to a method of treating disorders by administering to a patient in need of such treatment a therapeutically effective amount of a compound of formula (I): wherein R1-R8 are as described herein, R4 being aryl or heteroaryl.

USING ALKYLMETAL REAGENTS FOR DIRECTED METALATION OF AZAAROMATICS

Substituted alkylmetal reagents such as (trimethylsilylmethyl)lithium are reacted with azaaromatic compounds and/or nitrogen heterocycle compounds to produce functionalized azaaromatic compounds and functionalized nitrogen heterocycle compounds.