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2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 163119-30-0 Structure
  • Basic information

    1. Product Name: 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole
    2. Synonyms: 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl]thio]-1H-benziMidazole N-Oxide;2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole;Lansoprazole Sulfide N-Oxide;Lansoprazole IMpurity-Sulfone (EP-IMpurity B);1-methyl-12-thioxobenzo[4',5']imidazo[2',1':2,3]imidazo[1,5-a] pyridin-2(12H)-one;Lansoprazole Impurity K(Lansoprazole Sulfide N-Oxide)
    3. CAS NO:163119-30-0
    4. Molecular Formula: C16H14F3N3O2S
    5. Molecular Weight: 367.3455896
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 163119-30-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. CAS DataBase Reference: 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole(163119-30-0)
    11. EPA Substance Registry System: 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole(163119-30-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 163119-30-0(Hazardous Substances Data)

163119-30-0 Usage

Uses

Used in the preparation of Lansoprazole and its metabolite and impurities.

Check Digit Verification of cas no

The CAS Registry Mumber 163119-30-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,1,1 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 163119-30:
(8*1)+(7*6)+(6*3)+(5*1)+(4*1)+(3*9)+(2*3)+(1*0)=110
110 % 10 = 0
So 163119-30-0 is a valid CAS Registry Number.

163119-30-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Lansoprazole Sulfide N-Oxide

1.2 Other means of identification

Product number -
Other names 2-[[3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methylsulfanyl]-1H-benzimidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:163119-30-0 SDS

163119-30-0Relevant articles and documents

Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drug

Reddy, Ganta Madhusudhan,Mukkanti,Kumar, T. Laxmi,Babu, J. Moses,Reddy, Padi Pratap

, p. 3477 - 3489 (2008/12/23)

Lansoprazole (Prevacid) is an antiulcerative drug used for the treatment of duodenal and gastric ulcers, reflux oesophagitis, and Zollinger-Ellison syndrome. During the bulk synthesis of lansoprazole, we have observed five impurities: lansoprazole N-oxide, lansoprazole sulfone N-oxide, lansoprazole sulfide, lansoprazole sulfone and N-aralkyl lansoprazole. The present work describes the synthesis and characterization of these impurities. Copyright Taylor & Francis Group, LLC.

Efficient synthesis of N-Oxide derivatives: Substituted 2-(2-(pyridyl-N-oxide)methylsulphinyl)benzimidazoles

Ray, Purna C.,Mittapelli, Vasantha,Rohatgi, Amit,Tyagi, Om Dutt

, p. 2861 - 2868 (2008/02/12)

Different substituted 2-chloromethylpyridyl derivatives (6a-d) were oxidized with mCPBA to give the respective 2-chloromethylpyridine-N-oxide derivatives (7a-d) at low temperature, which on condensation with 2-mercapto-1H-benzimidazole (8a-c) in the presence of aprotic solvents give the 2-[[(pyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzimidazole (9a-d) in good yield. Finally, 9a-d oxidized with mCPBA in chlorinated solvent gives a mixture of 2-[[(pyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole (3a-d, 10%) and 2-[[(pyridin-2-yl-1-oxide) methyl]sulfinyl]-1H-benzimidazole (4a-d, 90%) derivatives. Copyright Taylor & Francis Group, LLC.

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