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4''-Pentyl-3-fluorobiphenyl-4-boronic acid is a complex chemical compound that serves as an intermediate in organic synthesis and high-throughput screening. It is characterized by its white or off-white solid appearance. The fluorine atom in its structure is valued in medicinal chemistry for its biocompatibility, stability, and its capacity to influence chemical properties. The boronic acid group is crucial for Suzuki coupling reactions, which are essential for carbon-carbon bond formation in the synthesis of pharmaceuticals and fine chemicals. The pentyl group, a five-carbon alkyl functional group, contributes to increased lipophilicity, potentially enhancing bioavailability in drug molecules.

163129-14-4

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163129-14-4 Usage

Uses

Used in Pharmaceutical Synthesis:
4''-Pentyl-3-fluorobiphenyl-4-boronic acid is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its fluorine atom and boronic acid group facilitate the creation of new carbon-carbon bonds through Suzuki coupling reactions, which are vital for constructing complex drug molecules.
Used in Organic Synthesis:
In the field of organic synthesis, 4''-Pentyl-3-fluorobiphenyl-4-boronic acid is used as a building block for the assembly of more complex organic molecules. Its pentyl group enhances lipophilicity, which can be beneficial for the solubility and bioavailability of the synthesized compounds.
Used in High-Throughput Screening:
4''-Pentyl-3-fluorobiphenyl-4-boronic acid is employed in high-throughput screening processes to identify potential drug candidates. Its unique structural features allow for the rapid evaluation of its interactions with biological targets, speeding up the drug discovery process.
Used in Fine Chemicals Production:
In the production of fine chemicals, 4''-Pentyl-3-fluorobiphenyl-4-boronic acid is used as a precursor to create specialty chemicals with specific applications, such as in the fragrance, flavor, or dye industries. Its versatility in synthesis makes it a valuable component in the creation of these精细化化学品 (fine chemicals).

Check Digit Verification of cas no

The CAS Registry Mumber 163129-14-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,1,2 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 163129-14:
(8*1)+(7*6)+(6*3)+(5*1)+(4*2)+(3*9)+(2*1)+(1*4)=114
114 % 10 = 4
So 163129-14-4 is a valid CAS Registry Number.

163129-14-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-fluoro-4-(4-pentylphenyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names 3-FLUORO-4'-PENTYLBIPHENYL-4-YLBORONIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:163129-14-4 SDS

163129-14-4Relevant academic research and scientific papers

Synthesis and mesomorphic properties of laterally fluorinated alkyl 4′′-alkylterphenyl-4-yl carbonate liquid crystals

Choluj, Artur,Kula, Przemyslaw,Dabrowski, Roman,Tykarska, Marzena,Jaroszewicz, Leszek

, p. 891 - 900 (2014)

Fifteen series of homologues of a variety of mono-, di- and trifluorosubstituted alkyl 4′′-alkylterphenyl-4-yl carbonates have been synthesized and their mesomorphic properties have been determined. From among 95 prepared compounds, 40 pure nematogens have been found, as well as 55 mesogens with orthogonal and tilted smectic phases in broad temperature ranges. The type and combination of the LC phase strongly depend on the position and number of the fluorine atoms. Physical properties and correlations between the molecular core fluorosubstitution, the length of the terminal chains and the type and sequence of the liquid crystalline phases, have been determined. The compounds are useful for the formulation of nematic mixtures as well as ferroelectric ones.

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