1632146-95-2Relevant academic research and scientific papers
Serendipitous discovery of a cascade approach to perhydrodibenzofuranones related to the natural product incarviditone
Christou, Stephania,Edwards, Alyn C.,Pritchard, Robin G.,Quayle, Peter,Stratford, Ian J.,Whitehead, Roger C.
supporting information, p. 1263 - 1266 (2014/06/10)
The unexpected discovery of an eliminative deprotection and cyclodimerization cascade reaction sequence led to the preparation of a series of perhydrodibenzofuranones that bear a structural resemblance to the natural product incarviditone. One of the novel dimers was found to show significant antiproliferative activity towards a non-small-cell lung cancer cell line, and represents a useful lead compound for the discovery of more potent anti-cancer agents.Georg Thieme Verlag Stuttgart. New York.
