1632149-89-3Relevant academic research and scientific papers
Prins Cyclization Using Magnesium Halides: Mild Access to 4-Halogenated Polysubstituted Tetrahydropyrans with a Special Feature
Walter, Mario,Schinzer, Dieter
, p. 817 - 820 (2014/04/03)
Different 4-halo-substituted polyfunctionalized tetra?hydropyrans were easily synthesized by segment-coupling Prins cyclization utilizing magnesium halides. The moderate Lewis acidity allows transformation of substrates bearing acid-labile functional groups. A solvent dependency of the stereochemistry at the C4 carbon was observed. Georg Thieme Verlag Stuttgart, New York.
