1632164-75-0Relevant academic research and scientific papers
Convenient synthesis of 5-arylidene-2-imino-4-thiazolidinone derivatives using microwave irradiation
Sarkis, Manal,Tran, Diem-Ngan,Dasso Lang, Maria Chiara,Garbay, Christiane,Braud, Emmanuelle
, p. 1257 - 1262 (2014/06/10)
A concise approach for the preparation of 5-arylidene-2-imino-4- thiazolidinone derivatives is described. Structurally diverse amines, isothiocyanates, aldehydes, and chloroacetyl chloride were combined under microwave irradiation to afford new 5-arylidene-2-imino-4-thiazolidinone derivatives. The one-pot synthesis involves the in situ formation of a thiourea followed by reaction with chloroacetyl chloride and an aldehyde to generate the target compounds. Georg Thieme Verlag Stuttgart New York.
