16322-14-8Relevant articles and documents
Enantioselective Synthesis of 4-Aminotetrahydroquinolines via 1,2-Reductive Dearomatization of Quinolines and Copper(I) Hydride-Catalyzed Asymmetric Hydroamination
Xu-Xu, Qing-Feng,Zhang, Xiao,You, Shu-Li
supporting information, p. 5357 - 5362 (2019/09/06)
A 1,2-reductive dearomatization of quinolines and copper(II) acetate monohydrate/(R,R)-Ph-BPE/P(p-tolyl)3-catalyzed enantioselective hydroamination sequence was developed, affording diverse 4-amino-1,2,3,4-tetrahydroquinolines with high levels of enantioselectivity in either a stepwise or one-pot fashion. Pleasingly, internal cis-cyclic alkenes, which are challenging substrates in copper hydride-catalyzed enantioselective hydroamination reactions, were transformed efficiently under mild conditions.
Depressant 1,2-dihydroquinolines and related derivatives.
Muren,Weissman
, p. 49 - 53 (2007/10/07)
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