163224-06-4Relevant academic research and scientific papers
An efficient one-pot synthesis of oxime ethers from alcohols using triphenylphosphine/carbon tetrachloride
Soltani Rad, Mohammad Navid,Khalafi-Nezhad, Ali,Karimitabar, Fatemeh,Behrouz, Somayeh
experimental part, p. 1724 - 1730 (2010/07/08)
A convenient and efficient one-pot O-alkylation of oximes from alcohols using triphenylphosphine in carbon tetrachloride is described. In this method, treatment of alcohols with a mixture of triphenylphosphine, carbon tetrachloride, oxime, and DBU in the presence of catalytic amounts of tetrabutylammonium iodide in refluxing acetonitrile regioselectively furnishes the corresponding O-alkyl ethers in good yields. This methodology is highly efficient O-alkylation of oximes with various structurally diverse alcohols. Semiempirical quantum-mechanic calculations (AM1) for unsymmetrical oxime ethers, indicated a lower heat of formation for Z-isomers. Georg Thieme Verlag Stuttgart - New York.
Organoselenium-induced Stereoselective Cyclisation of O-Allyl Oximes: A New Synthetic Route to Isoxazolidines
Tiecco, Marcello,Testaferri, Lorenzo,Tingoli, Marco,Bagnoli, Luana
, p. 235 - 236 (2007/10/02)
The organoselenium-induced ring-closure reactions of O-allyl oximes give cyclic iminium salts which react with water to afford isoxazolidines in good yield.
