16323-88-9

Upstream product

• 123-72-8 butyraldehyde 
• 62-53-3 aniline 
• 122-52-1 triethyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 
• 762-04-9 Diethyl phosphonate 
• 123-38-6 propionaldehyde 

Relevant academic research and scientific papers

Poly(4-vinylpyridine)-supported dual acidic ionic liquid: A novel heterogeneous catalyst for the synthesis of β-Acetamido ketones

Asupported dual acidic ionic liquid catalystwas easily prepared from its startingmaterials and used as an environmentally friendly heterogeneous catalytic system for the synthesis of β-acetamido ketones from the four-component condensation of an aromatic aldehyde with acetophenone, acetyl chloride, and acetonitrile at room temperature. This catalyst was also applied as an efficient catalyst for the synthesis of α-aminophosphonates. The catalyst favorably combines the properties of ionic liquids and advantages of solid supports and is recoverable without loss in its catalytic activity. Copyright Taylor & Francis Group, LLC.

A novel hydrophobic copper complex supported on γ-Fe2O3 as a magnetically heterogeneous catalyst for one-pot three-component synthesis of α-aminophosphonates

A novel hydrophobic copper complex supported on γ-Fe2O3 is synthesized and characterized by different methods such as FT-IR, XRD, TEM, SEM, TGA, VSM, ICP and CHN analysis. It was used as a magnetically recyclable heterogeneous cataly

Synthesis of α-aminophosphonates using carbon nanotube supported imidazolium salt-based ionic liquid as a novel and environmentally benign catalyst

A supported acidic catalyst was easily prepared via anchoring imidazolium salt-based ionic liquid onto multiwalled carbon nanotube by covalent bonds. This novel immobilized acidic ionic liquid effectively catalyzed the one-pot synthesis of α-aminophosphonates from the reaction of amines and aldehydes with diethyl phosphite. The catalyst can be easily recovered and reused without appreciable change in its efficiency.

Iron-doped single walled carbon nanotubes as an efficient and reusable heterogeneous catalyst for the synthesis of organophosphorus compounds under solvent-free conditions

Iron-doped single walled carbon nanotubes (Fe/SWCNTs) is an efficient, eco-friendly, and reusable heterogeneous catalyst for the synthesis of diversely decorated α-aminophosphonates via multicomponent reaction of amines, carbonyl compounds, and phosphorus compounds under solvent-free conditions. This methodology illustrates a very simple procedure, with wide applicability, extending the scope to aliphatic and aromatic amines and carbonyl compounds. It also enabled the development of one-pot synthesis of β-phosphonomalonates during the reaction of carbonyl compounds, malononitrile and phosphorus compounds. Excellent results were obtained in each case affording the corresponding organophosphorus adducts in good yields.

Synthesis of α-aminophosphonates using polystyrene supported Al(OTf)3 as a heterogeneous catalyst

A mild and efficient method has been devised for the preparation of -aminophosphonates from three component condensation of an aldehyde, an amine, and diethyl phosphite in the presence of catalytic amounts of cross-linked polystyrene supported aluminium triflate (Ps-Al(OTf)3) under solvent-free conditions in good to excellent yields. The catalyst is stable (as a bench top catalyst) and can be easily recovered and reused without appreciable change in its efficiency. Taylor & Francis Group, LLC.

Titanocene dichloride as an efficient catalyst for one-pot synthesis of α-aminophosphonates

Commercially available titanocene dichloride was firstly used as an extremely efficient catalyst for a three-component one-pot reaction of an amine, an aldehyde (ketone), and a dialkyl phosphite to form α-aminophosphonates under solvent-free conditions at

Metal-free multicomponent synthesis of (α-aminoalkyl)phosphonates using 2,4,6-trichloro-1,3,5-triazine

(α-Aminoalkyl)phosphonates have efficiently been synthesized by multicomponent reaction of aldehydes, amines, and triethyl phosphite in the presence of 2,4,6-trichloro-1,3,5-triazine at room temperature. The products are formed in high yields (83-91%) within 0.5-1h. Copyright

Silica gel and polystyrene supported aluminum chloride as heterogeneous catalysts for the preparation of α-aminophosphonates

Silica gel supported aluminum chloride (SiO2-AlCl3) and cross-linked polystyrene-supported aluminum chloride (PS-AlCl3) are environment- friendly heterogeneous catalysts for the condensation of amines and aldehydes with diethyl phosphite to afford α-aminophosphonates. These solid acid catalysts are stable (as bench top catalysts) and can be easily recovered and reused without appreciable change in their efficiency.

Micellar solution of sodium dodecyl sulfate (SDS) catalyzes Kabacknik-Fields reaction in aqueous media

A new, convenient and high-yielding procedure for the one-pot synthesis of diethyl α-aminophosphonates from aldehydes, amines and diethyl phosphite (Kabacknik-Fields reaction) in SDS micellar solution in aqueous media is described. The synthesis of aaminophosphonates in the present study represents a three-component reaction in which no intermediate formation of either an imine or α-hydroxyphosphonate was observed. Georg Thieme Verlag Stuttgart.

Mesoporous aluminosilicate nanocage-catalyzed three-component coupling reaction: an expedient synthesis of α-aminophosphonates

Here we demonstrate for the first time the synthesis of α-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excell