163352-70-3Relevant academic research and scientific papers
TAUTOMERISM OF β-KETOESTER ACYLHYDRAZONES
Yakimovich, S. I.,Zelenin, K. N.,Zerova, I. V.
, p. 1339 - 1344 (2007/10/02)
β-Ketoester acylhydrazones exist in solution as tautomeric mixtures of the hydrazone and conjugate enehydrazine forms.The equilibrium shifts toward the hydrazone form upon introducing an α-substituent or an ester group at the C=N bond.The contribution of the enehydrazine tautomer increases when the α- and β-substituents in the β-dicarbonyl component constitute a common ring system, when the N-aroyl group contains a donor substituent, and also with increasing size of the substituent in the N-acyl moiety and in strongly polar basic solvents.
