1634-53-3

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-1-(5-methylfuran-2-yl)-ethanone is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-1-(5-methylfuran-2-yl)-ethanone serves as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can be utilized in agricultural practices for pest control and crop protection.
Used in Organic Synthesis:
2-Bromo-1-(5-methylfuran-2-yl)-ethanone is utilized as a building block in organic synthesis, enabling the construction of a variety of bioactive molecules that can be further explored for their potential applications in medicine and other fields.
Used in Chemical Research:
2-Bromo-1-(5-methylfuran-2-yl)-ethanone is also used as a reagent in chemical research, particularly for the development of new chemical reactions and transformations, contributing to the advancement of synthetic chemistry and the discovery of novel chemical processes.

Upstream product

• 1193-79-9 2-acetyl-5-methylfuran 

Downstream Products

• 1634-46-4 4-(5-methylfuran-2-yl)thiazol-2-amine 

Relevant academic research and scientific papers

Bromination of 2-acetyl-5-methylfuran

The bromination of 2-acetyl-5-methylfuran by bromine and N-bromosuccinimide was studied. The action of N-bromosuccinimide on 5-methyl-2-acetylfuran in various solvents leads to mixtures of an ω-bromo ketone, a 5-bromomethyl derivative, and 5-bromomethyl-ω-bromo ketone. The use of 2,2′-azobisisobutyronitrile as activator of the radical process does not make the reaction selective but promotes bromination at the methyl group of the ring. A selective method for the synthesis of 2-(bromoacetyl)-5-methylfuran by the bromination of 2-acetyl-5-methylfuran with bromine was developed. 1999 KluwerAcademic/Plenum.

Substituted thiazole derivative and application thereof

The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.

UREA DERIVATIVES METHODS FOR THEIR MANUFACTURE AND USES THEREOF

The present invention provides compounds of formula (I): in which R 1, R'1, R2, R'2, R3, Y and G have the meanings given in the description, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.

HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.

Pyridoquinoxaline antivirals

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof wherein R1, R2 and R3 are as defined in the specification. The compounds are useful for the treatment of viral infections.

Reaction of N,N-dialkylcarboxamides with halogens

N,N-Dialkylcarboxamides react with halogens in the absence of water to form complexes which are likely to have an ionic structure with the Hlg+ ion coordinated at the carbonyl oxygen atom. These products can be isolated as individual compounds.