163438-06-0 Usage
Description
(S)-(+)-N-(1-(1-NAPHTHYL)ETHYL)PHTHALAM&, also known as (S)-(+)-N-Acetyl-1-naphthyl ethylamine, is a chiral chemical compound with the molecular formula C20H16NO2. It exists as a white crystalline solid at room temperature and has a wide range of applications in the field of pharmaceuticals and organic synthesis.
Uses
Used in Pharmaceutical Industry:
(S)-(+)-N-(1-(1-NAPHTHYL)ETHYL)PHTHALAM& is used as a chiral auxiliary in asymmetric synthesis for controlling the stereochemistry of reactions. Its unique structure and properties make it a valuable compound in the development of new drugs and pharmaceutical products.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-(+)-N-(1-(1-NAPHTHYL)ETHYL)PHTHALAM& serves as a reagent in the synthesis of various biologically active compounds. Its ability to control stereochemistry in reactions contributes to the creation of complex organic molecules with specific properties and applications.
Used in Research and Development:
(S)-(+)-N-(1-(1-NAPHTHYL)ETHYL)PHTHALAM& is also utilized in research and development for its potential in creating novel chemical compounds and exploring new reaction pathways. Its unique properties make it an interesting subject for further study and potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 163438-06-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,4,3 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 163438-06:
(8*1)+(7*6)+(6*3)+(5*4)+(4*3)+(3*8)+(2*0)+(1*6)=130
130 % 10 = 0
So 163438-06-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H17NO3/c1-13(15-12-6-8-14-7-2-3-9-16(14)15)21-19(22)17-10-4-5-11-18(17)20(23)24/h2-13H,1H3,(H,21,22)(H,23,24)/t13-/m0/s1
163438-06-0Relevant articles and documents
Probing enzyme stereospecificity. Inhibition of α-chymotrypsin and subtilisin Carlsberg by chiral amine- and aminoalcohol-derivatives
Occhiato, Ernesto,Jones, J. Bryan
, p. 4199 - 4214 (2007/10/03)
Various enantiomeric amine and aminoalcohol amide and α-ketoamide derivatives have been evaluated as competitive inhibitors of the representative serine proteases α-chymotrypsin (CT) and subtilisin Carlsberg (SC). Each compound studied was an effective competitive inhibitor of both enzymes. However, only for the best inhibitor, N-pyruvoyl-1-(1-naphthyl)ethylamine (K1 27 μM for the S-enantiomer with CT), was noteworthy enantiomeric discrimination manifest, with the S-enantiomer being a significantly more powerful inhibitor of CT and SC than its R-counterpart by factors of 12.6- and 73-fold, respectively. The enzyme-inhibitor interactions responsible for this strong binding and enantiomeric discrimination were revealed by molecular modelling analyses.
