163461-02-7

Basic information

• Product Name: 2-Thiophenecarboxaldehyde, 4-(1-methylethyl)- (9CI)
• Synonyms: 2-Thiophenecarboxaldehyde, 4-(1-methylethyl)- (9CI)
• CAS NO: 163461-02-7
• Molecular Formula: C8H10OS
• Molecular Weight: 154.2294
• Product Categories: ALDEHYDE;ISOPROPYL
• Mol File: 163461-02-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 240.4±28.0 °C(Predicted)
• Appearance: /
• Density: 1.096±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Thiophenecarboxaldehyde, 4-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxaldehyde, 4-(1-methylethyl)- (9CI)(163461-02-7)
• EPA Substance Registry System: 2-Thiophenecarboxaldehyde, 4-(1-methylethyl)- (9CI)(163461-02-7)

Safety Data

• Hazardous Substances Data: 163461-02-7(Hazardous Substances Data)

Upstream product

• 29488-27-5 3-isopropylthiophene 
• 68-12-2 N,N-dimethyl-formamide 
• 42908-63-4 3-(prop-1-en-2-yl)thiophene 

Relevant articles and documents

STUDIES TOWARD ALKYLTHIOPHENE-2-CARBOXALDEHYDES. REDUCTION OF 3-ALKENYLTHIOPHENES WITH TRIETHYLSILANE/TRIFLUOROACETIC ACID. REGIOSELECTIVTY IN FORMYLATION REACTIONS OF ALKYLTHIOPHENES

Reduction of 2- or 3-alkenylthiophenes with Et3SiH/CF3CO2H in CH2Cl2 gives the corresponding 2- or 3-alkylthiophene in >90percent isolated yield.The regioselectivity of various Vilsmeier formylations of 3-alkylthiophenes was found to be a function of increasing steric bulk in the 3-alkyl substituent and in the Vilsmeier reagent.The regioselectivty of formylations of 3-alkylthiophenes by initial lithiation with butyllithium in ether followed quenching with DMF is independent of the presence or absence of TMEDA.