163517-56-4

Basic information

• Product Name: 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE
• Synonyms: 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE;2-TOLYLBORONIC ACID, PROPANEDIOL CYCLIC ESTER;2-METHYLPHENYLBORONIC ACID, PROPANEDIOL CYCLIC ESTER;2-METHYLBENZENEBORONIC ACID, PROPANEDIOL CYCLIC ESTER;AKOS BRN-0795;2-Methylbenzeneboronic acid, propanediol cyclic ester 95%;2-Methylbenzeneboronic acid 1,3-propanediol ester, 95%;2-Methylbenzeneboronicacid,propanediolcyclicester95%
• CAS NO: 163517-56-4
• Molecular Formula: C10H13BO2
• Molecular Weight: 176.02
• Product Categories: blocks;BoronicAcids
• Mol File: 163517-56-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 300.229 °C at 760 mmHg
• Flash Point: 135.374 °C
• Appearance: /
• Density: 1.028 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE(163517-56-4)
• EPA Substance Registry System: 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE(163517-56-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 163517-56-4(Hazardous Substances Data)

Usage

General Description

2-(2-Methylphenyl)-1,3,2-dioxaborinane is a chemical compound that belongs to the class of dioxaborinane derivatives. It is a boron-containing compound that is commonly used as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds. 2-(2-METHYLPHENYL)-1,3,2-DIOXABORINANE is known for its stability and effectiveness in various chemical reactions, making it a valuable tool in the field of organic chemistry. Additionally, it is also used in the pharmaceutical industry for the synthesis of various drug molecules and is considered to be a versatile building block for the creation of new chemical entities with potential biological activity.

InChI:InChI=1/C10H13BO2/c1-9-5-2-3-6-10(9)11-12-7-4-8-13-11/h2-3,5-6H,4,7-8H2,1H3

Upstream product

• 16419-60-6 2-Methylphenylboronic acid 
• 504-63-2 trimethyleneglycol 

Downstream Products

• 605-39-0 2,2'-dimethyl-1,1'-biphenyl 

Relevant articles and documents

Copper(i)-catalyzed amidation reaction of organoboronic esters and isocyanates

A simple and efficient methodology for the preparation of amides from easily available organoboronic esters and isocyanates has been accomplished using a ligand-free copper(i) catalyst. The reaction system demonstrated a broad substrate scope and provided convenient access to a wide variety of secondary amides.

Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates

A Ru-catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combinations of N-(2-pyridyl) substituted benzylamines and arylboronates. Substitution of the pyridine directing group in the 3-position proved to be crucial in order to achieve high arylation yields. Furthermore, the pyridine directing group can be removed in high yields via a two-step protocol.

Preparation process for beta-alkoxy acrylic acid

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