163527-43-3Relevant articles and documents
Hypoxia-Selective Antitumor Agents. 10. Bis(nitroimidazoles) and Related Bis(nitroheterocycles): Development of Derivatives with Higher Rates of Metabolic Activation under Hypoxia and Improved Aqueous Solubility
Hay, Michael P.,Lee, Ho H.,Wilson, William R.,Roberts, Peter B.,Denny, William A.
, p. 1928 - 1941 (2007/10/02)
A series of analogues of the prviously described compound N--4-(2-nitroimidazol-1H-yl)butanamide (4), a novel hypoxic cell cytotoxin and radiosensitizer, have been prepared and evaluated for hypoxia-selective cytot