163560-68-7

Upstream product

• 99972-42-6 1-phenyl-1H-pyrrole-3-carboxylic acid 
• 100-51-6 benzyl alcohol 
• 220968-56-9 1-Phenyl-1H-pyrrole-3-carbonyl chloride 
• 62-53-3 aniline 
• 120777-22-2 1-phenyl-1H-pyrrole-3-carbaldehyde 
• 163560-67-6 1-phenylpyrrole-3-carboxylic acid azide 

Downstream Products

• 691863-04-4 methanesulfonic acid 2-oxo-3-(1-phenyl-1H-pyrrol-3-yl)-oxazolidin-5-ylmethyl ester 
• 691863-16-8 5-azidomethyl-3-(1-phenyl-1H-pyrrol-3-yl)-oxazolidin-2-one 
• 691863-28-2 5-aminomethyl-3-(1-phenyl-1H-pyrrol-3-yl)-oxazolidin-2-one 
• 691862-92-7 5-hydroxymethyl-3-(1-phenyl-1H-pyrrol-3-yl)-oxazolidin-2-one 
• 163560-69-8 3-amino-1-phenylpyrrole 

Relevant academic research and scientific papers

Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480

Pursuing our search program for new antitubercular drugs we decided to explore the potentiality of oxazolidinone moiety by synthesizing novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480. The new derivatives were tested against atypical mycobacteria as well as against drug resistant Mycobacterium tuberculosis and some of them exhibited a fairly good activity against Mycobacterium avium complex (MAC).