163617-92-3

Basic information

• Product Name: 1-(1-adamantyl)methylamino-2-nitrobenzene
• Synonyms: 1-(1-adamantyl)methylamino-2-nitrobenzene
• CAS NO: 163617-92-3
• Molecular Weight: 286.374
• Mol File: 163617-92-3.mol

Chemical Properties

• CAS DataBase Reference: 1-(1-adamantyl)methylamino-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-adamantyl)methylamino-2-nitrobenzene(163617-92-3)
• EPA Substance Registry System: 1-(1-adamantyl)methylamino-2-nitrobenzene(163617-92-3)

Safety Data

• Hazardous Substances Data: 163617-92-3(Hazardous Substances Data)

Upstream product

• 2094-72-6 1-Adamantanecarbonyl chloride 
• 88-74-4 2-nitro-aniline 
• 163617-91-2 1-(1-adamantyl)carbonylamino-2-nitrobenzene 

Downstream Products

• 163618-30-2 N-{1-(1-adamantyl)methyl-2,4-dioxo-5-[2-(pyrrolidin-1-yl)ethyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl}-N'-phenylurea 
• 163618-39-1 N-{1-(1-adamantyl)methyl-2,4-dioxo-5-[2-(morpholin-4-yl)ethyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl}-N'-phenylurea 
• 163617-97-8 1-(1-adamantyl)methyl-2,4-dioxo-5-[2-(pyrrolidin-1-yl)ethyl]-3-phenylhydrazono-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 163617-94-5 1-(1-adamantyl)methyl-2,4-dioxo-5-[2-(morpholin-4-yl)ethyl]-3-phenylhydrazono-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 163617-96-7 N-(1-adamantyl)methyl-N'-[2-(1-pyrrolidino)ethyl]-1,2-phenylenediamine 
• 163617-93-4 N-(1-adamantyl)methyl-N'-[2-(morpholin-4-yl)ethyl]-1,2-phenylenediamine 
• 1322056-30-3 2-tert-butoxycarbonylamino-N-([1-(1-adamantylmethyl)-5-[2-(morpholin-4-yl)ethyl]-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl])-3-phenylpropionamide 
• 206360-70-5 {(R)-2-[5-Adamantan-1-ylmethyl-2,4-dioxo-3-(3-phenyl-ureido)-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-yl]-1-hydroxymethyl-ethyl}-carbamic acid tert-butyl ester 
• 206360-68-1 (R)-4-[5-Adamantan-1-ylmethyl-2,4-dioxo-3-(phenyl-hydrazono)-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 206360-67-0 (R)-4-({2-[(Adamantan-1-ylmethyl)-amino]-phenylamino}-methyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 160917-85-1 N₁-(1-adamantyl)methyl-1,2-phenylenediamine 

Relevant articles and documents

Diastereomeric separation of 1,5-benzodiazepines due to the presence of a chiral centre on the N-5 alkylic chain

The presence of a chain bearing a stereogenic centre at the N-5 position of 1-(1-adamantylmethyl)-3-arylureido-2,4-dioxo-1,5-benzodiazepines induces optical resolution. The synthesis of these compounds and their potency as potential CCK-B receptor antagonists is discussed briefly here.

Synthesis and structure-activity relationship of new 1,5-dialkyl-1,5- benzodiazepines as cholecystokinin-2 receptor antagonists

This article deals with the synthesis and the activities of some 1,5-dialkyl-3-arylureido-1,5-benzodiazepin-2,4-diones which were prepared as potential CCK2 antagonists, with the intention to find a possible follow up of our lead compound GV150013, showin