163630-79-3
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Basic information
- Product Name: Lu 28-179
- Synonyms: Lu 28-179;1′-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4′-piperidine] fumarate salt;Siramesine fumarate salt;Siramesine (fumarate)
- CAS NO:163630-79-3
- Molecular Formula: C34H35FN2O5
- Molecular Weight: 570.6505032
- EINECS: N/A
- Product Categories: N/A
- Mol File: 163630-79-3.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: white to beige/
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: DMSO: soluble20mg/mL, clear
- CAS DataBase Reference: Lu 28-179(CAS DataBase Reference)
- NIST Chemistry Reference: Lu 28-179(163630-79-3)
- EPA Substance Registry System: Lu 28-179(163630-79-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 163630-79-3(Hazardous Substances Data)
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163630-79-3 Usage
Biochem/physiol Actions
Siramesine is a blood-brain barrier penetrant, selective and potent sigma-2 receptor agonist, which exhibits potent and very long-lasting anxiolytic effects in rodents. Also, siramesine is a lysosome-destabilizing agent that causes lysosomal cell death in varies immortalized and cancer cell lines.Check Digit Verification of cas no
The CAS Registry Mumber 163630-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,6,3 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.Calculate Digit Verification of CAS Registry Number 163630-79:
(8*1)+(7*6)+(6*3)+(5*6)+(4*3)+(3*0)+(2*7)+(1*9)=133
133 % 10 = 3
So 163630-79-3 is a valid CAS Registry Number.
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Lu 28-179
