163667-46-7Relevant academic research and scientific papers
PYRAZOLO[1,5-a]PYRIMIDINE COMPOUND
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, (2018/08/01)
The compounds represented by formulas (I) to (XVIII) or pharmaceutically acceptable salts thereof.
Asymmetric Transfer Hydrogenation of Imines using Alcohol: Efficiency and Selectivity are Influenced by the Hydrogen Donor
Pan, Hui-Jie,Zhang, Yao,Shan, Chunhui,Yu, Zhaoyuan,Lan, Yu,Zhao, Yu
supporting information, p. 9615 - 9619 (2016/08/10)
The influence of the alcohol, as the hydrogen donor, on the efficiency and selectivity of the asymmetric transfer hydrogenation (ATH) of imines is reported for the first time. This discovery not only leads to a highly enantioselective access to N-aryl and N-alkyl amines, but also provides new insight into the mechanism of the ATH of imines. Both experimental and computational studies provide support for the reaction pathway involving an iridium alkoxide as the reducing species.
Towards a practical br?nsted acid catalyzed and hantzsch ester mediated asymmetric reductive amination of ketones with benzylamine
Wakchaure, Vijay N.,Nicoletti, Marcello,Ratjen, Lars,List, Benjamin
supporting information; experimental part, p. 2708 - 2710 (2011/02/16)
We report the use of benzylamine as the amine component in Hantzsch ester mediated and chiral Br?nsted acid catalyzed enantioselective reductive aminations of ketones. The method is noteworthy because the benzyl group is easily removable, and amine product purification is achieved through Hantzsch ester oxidation product removal via basic hydrolysis.
