163671-16-7

Upstream product

• 20924-05-4 thymidyl acetic acid 
• 151953-64-9 (3R,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}pyrrolidine-3-ol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 202127-35-3 1-[2-((2S,4R)-4-Hydroxy-2-hydroxymethyl-pyrrolidin-1-yl)-2-oxo-ethyl]-5-methyl-1H-pyrimidine-2,4-dione 
• 163671-10-1 9-fluorenylmethyloxycarbonyl-5-(4,4'dimethoxytrityloxy)methyl-3-hydroxypyrrolidine 
• 163671-09-8 N-Fmoc-3R-hydroxypyrrolidine-5S-methanol 
• 88050-17-3 N-Fmoc-trans-4-Hydroxy-L-Proline 

Downstream Products

• 163671-27-0 Diisopropyl-phosphoramidous acid (3R,5S)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-1-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-pyrrolidin-3-yl ester 2-cyano-ethyl ester 

Relevant academic research and scientific papers

Synthesis and properties of pyrrolidine-based negatively charged dna mimics

A set of novel chiral pyrrolidine-based nucleotide mimics, in which nucleobase, hydroxyl group and phosphonic acid residue were attached to different carbon atoms of the pyrrolidine ring, was synthesized. These monomers were used for the synthesis of the

Synthesis of N-substituted hydroxyprolinol phosphoramidites for the preparation of combinatorial libraries

A series of N-substituted DMT-hydroxymethylpyrrolidinol phosphoramidites has been prepared from trans-4-hydroxyproline. These can be coupled in high yield and purity using automated synthesis techniques, allowing a wide range of functionalities to be intr