163671-30-5

Upstream product

• 88050-17-3 N-Fmoc-trans-4-Hydroxy-L-Proline 
• 163671-10-1 9-fluorenylmethyloxycarbonyl-5-(4,4'dimethoxytrityloxy)methyl-3-hydroxypyrrolidine 
• 151953-64-9 (3R,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}pyrrolidine-3-ol 
• 163671-09-8 N-Fmoc-3R-hydroxypyrrolidine-5S-methanol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 163671-19-0 (3R,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-1-methanesulfonyl-pyrrolidin-3-ol 

Relevant academic research and scientific papers

Synthesis of N-substituted hydroxyprolinol phosphoramidites for the preparation of combinatorial libraries

A series of N-substituted DMT-hydroxymethylpyrrolidinol phosphoramidites has been prepared from trans-4-hydroxyproline. These can be coupled in high yield and purity using automated synthesis techniques, allowing a wide range of functionalities to be intr