1636897-35-2Relevant academic research and scientific papers
Metal-Free Nitration of the C(sp3)?H Bonds of 2-Oxindoles through Radical Coupling Reaction at Room Temperature
Wei, Wen-Ting,Zhu, Wen-Ming,Ying, Wei-Wei,Wang, Yi-Ning,Bao, Wen-Hui,Gao, Le-Han,Luo, Yun-Jie,Liang, Hongze
, p. 3551 - 3554 (2017/09/13)
A metal-free nitration of the C(sp3)?H bonds of 2-oxindoles with t-BuONO through radical coupling reaction at room temperature has been developed. Using t-BuONO both as a nitrating reagent and as an oxidant, to couple with the C(sp3)?H bonds of 2-oxindoles, thus forming a new C?N bond without using any other reagents. This reaction provides a green and straightforward approach to some useful 3-nitro-2-oxindoles in moderate to good yields. (Figure presented.).
Reduction of 3-aminoquinoline-2,4(1H,3H)-diones and deamination of the reaction products
Klásek, Antonín,Ly?ka, Antonín,Rouchal, Michal,Rudolf, Ond?ej,R??i?ka, Ale?
, p. 595 - 612 (2014/06/09)
3-Aminoquinoline-2,4-diones were stereoselectively reduced with NaBH 4 to give cis-3-amino-3,4-dihydro-4-hydroxyquinolin-2(1H)-ones. Using triphosgene (=bis(trichloromethyl) carbonate), these compounds were converted to 3,3a-dihydrooxazolo[4,5-
