16369-01-0

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 961-07-9 2'-Deoxyguanosine 

Downstream Products

• 4318-05-2 2-(acetylamino)-9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one 
• 190849-98-0 Carbonic acid (2R,3S,5R)-5-(2-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 1-(6-nitro-benzo[1,3]dioxol-5-yl)-ethyl ester 
• 100648-99-5 2'-Deoxy-N²-5'-O-bis(p,p'-dimethoxytrityl)guanosine 
• 146713-19-1 N²-dimethoxytrityl-5'-amino-2',5'-dideoxyguanosine 

Relevant academic research and scientific papers

Functionalization of solid supports with N-unprotected deoxyribonucleosides

N-Unprotected deoxyribonucleotides were loaded to solid supports via a succinyl or an oxalyl linker. These solid supports were successfully used for oligonucleotide synthesis by the H-phosphonate method without N-protecting groups.

Synthesis, Enzymatic Stability And Physicochemical Properties Of Oligonucleotides Containing A N-Cyanoguanidine Linkage.

Nucleoside dimers with a N-cyanoguanidine linkage were synthesized and used as building blocks for oligonucleotide synthesis.Oligonucleotides composed of alternating phosphodiester and cyanoguanidine functions are still able to hybridize with a complementary natural oligodeoxynucleotide.