16373-60-7

Basic information

• Product Name: (1R,3aS,3bS,9aR,9bS,11aR)-5-benzyl-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,3a,3b,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-4H-cyclopenta[i]phenanthridin-4-one
• Synonyms: 6-Azacholest-4-en-7-one, 6-benzyl-
• CAS NO: 16373-60-7
• Molecular Formula: C₃₃H₄₉NO
• Molecular Weight: 475.7483
• Mol File: 16373-60-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 596°C at 760 mmHg
• Flash Point: 254.1°C
• Density: 1.04g/cm³
• Vapor Pressure: 3.59E-14mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: (1R,3aS,3bS,9aR,9bS,11aR)-5-benzyl-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,3a,3b,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-4H-cyclopenta[i]phenanthridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3aS,3bS,9aR,9bS,11aR)-5-benzyl-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,3a,3b,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-4H-cyclopenta[i]phenanthridin-4-one(16373-60-7)
• EPA Substance Registry System: (1R,3aS,3bS,9aR,9bS,11aR)-5-benzyl-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,3a,3b,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-4H-cyclopenta[i]phenanthridin-4-one(16373-60-7)

Safety Data

• Hazardous Substances Data: 16373-60-7(Hazardous Substances Data)

Usage

General Description

The chemical (1R,3aS,3bS,9aR,9bS,11aR)-5-benzyl-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,3a,3b,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-4H-cyclopenta[i]phenanthridin-4-one, also known as (R)-(+)-mexiletine or mexiletine, is a class Ib antiarrhythmic medication used to treat ventricular arrhythmias. Mexiletine works by blocking sodium channels and reducing the irritability of the heart muscle. It is used to treat irregular heartbeats and to prevent sudden cardiac death in patients with certain heart conditions. Additionally, mexiletine has potential applications in pain management, particularly in controlling neuropathic pain.