1637436-82-8

Basic information

• Product Name: methyl (S)-2-acetyl-2-hydroxy-4-phenylpent-4-enoate
• CAS NO: 1637436-82-8
• Molecular Weight: 248.279
• Mol File: 1637436-82-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (S)-2-acetyl-2-hydroxy-4-phenylpent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-2-acetyl-2-hydroxy-4-phenylpent-4-enoate(1637436-82-8)
• EPA Substance Registry System: methyl (S)-2-acetyl-2-hydroxy-4-phenylpent-4-enoate(1637436-82-8)

Safety Data

• Hazardous Substances Data: 1637436-82-8(Hazardous Substances Data)

Upstream product

• 86396-16-9 methyl 2,3-dioxobutanoate 
• 98-83-9 isopropenylbenzene 
• 105-45-3 acetoacetic acid methyl ester 
• 24762-04-7 2-Diazo-3-oxo-butyric acid methyl ester 

Relevant articles and documents

Highly enantioselective carbonyl-ene reactions of 2,3-diketoesters: Efficient and atom-economical process to functionalized chiral α-hydroxy-β-ketoesters

Carbonyl-ene reactions of 2,3-diketoesters catalyzed by [Cu{(S,S)-tBu-box}](SbF6)2 [box=bis(oxazoline)] generate chiral α-functionalized α-hydroxy-β-ketoesters in up to 94% yield and 97% ee. The 2,3-diketoesters are conveniently accessed from the corresponding α-diazo-β-ketoester, and a catalyst loading as low as 1.0 mol% can be achieved.