1637438-98-2Relevant academic research and scientific papers
Iridium-catalyzed arylative cyclization of alkynones by 1,4-iridium migration
Partridge, Benjamin M.,Solana Gonzalez, Jorge,Lam, Hon Wai
supporting information, p. 6523 - 6527 (2014/06/24)
1,4-Metal migrations enable the remote functionalization of C-H bonds, and have been utilized in a wide variety of valuable synthetic methods. The vast majority of existing examples involve the 1,4-migration of palladium or rhodium. Herein, the stereoselective synthesis of complex polycycles by the iridium-catalyzed arylative cyclization of alkynones with arylboronic acids is described. To our knowledge, these reactions involve the first reported examples of 1,4-iridium migration.
