1637596-87-2Relevant academic research and scientific papers
Chemistry of polyhalogenated nitrobutadienes, 14: Efficient synthesis of functionalized (Z)-2-allylidenethiazolidin-4-ones
Zapol'skii, Viktor A.,Namyslo, Jan C.,Gjikaj, Mimoza,Kaufmann, Dieter E.
supporting information, p. 1638 - 1644 (2014/08/05)
The reaction of mercaptoacetic acid esters with pentachloro-2-nitro-1,3- butadiene (1) provides an appropriate precursor for the synthesis of special thiazolidin-4-ones. Applying different anilines as the second constituent for the requisite cyclization step, a series of (Z)-2-allylidenethiazolidin-4-ones was obtained in yields up to 81%. Some subsequent reactions have been examined too, such as the formation of perfunctionalized 1H-pyrazoles upon treatment with hydrazine. Thiazolidinones are as well known for their physiological activities as for their application in optoelectronics.
