163776-96-3Relevant academic research and scientific papers
Termination of carbopalladation of alkynes via carbonylative amidation producing lactams
Coperet, Christophe,Sugihara, Takumichi,Negishi, Ei-Ichi
, p. 1771 - 1774 (1995)
Trapping of acylpalladium derivatives can be achieved using internal carboxamides and sulfonamides, in addition to simple amines and applied to termination of carbopalladation to produce lactams.
Cyclic carbopalladation of alkynes terminated by carbonylative amidation
Coperet, Christophe,Ma, Shengming,Sugihara, Takumichi,Negishi, Ei-Ichi
, p. 11529 - 11544 (2007/10/03)
Termination of cyclic carbopalladation of alkynes via carbonylative lactamization can be achieved more satisfactorily with alkenyl or aryl halides containing an ω-carboxamido or ω-sulfonamido group than with those containing an ω-amino group. The method appears to be generally satisfactory for the preparation of fused cyclic systems consisting of six-membered rings, while the other cases require further development.
