1638143-36-8Relevant articles and documents
Copper-catalyzed Meerwein carboarylation of alkenes with anilines to form 3-benzyl-3-alkyloxindole
Tang, Shi,Zhou, Dong,Deng, Youlin,Li, Zhihao,Yang, You,He, Jianguang,Wang, Yingchun
, p. 684 - 688 (2015)
A simple and direct route for double C-C bond formation by copper-catalyzed Meerwein carboarylation process has been developed. In the presence of CuI (5 mol%), tert-butyl nitrite and anilines, a wide variety of N-arylacrylamides underwent tandem Meerwein arylation/C-H cyclization to produce pharmaceutically important 3-benzyl-3-alkyloxindole in moderate to good yield.
Metal-free meerwein carboarylation of alkenes with anilines: A straightforward approach to 3-benzyl-3-alkyloxindoles
Tang, Shi,Zhou, Dong,Wang, Ying-Chun
supporting information, p. 3656 - 3661 (2014/06/23)
A metal-free, straightforward carboarylation reaction of alkenes with anilines was developed that proceeds through a radical C-H cyclization. In the presence of benzoyl peroxide (5 mol-%), tert-butyl nitrite, and an array of anilines, a wide variety of N-arylacrylamides underwent a tandem Meerwein arylation/C-H cyclization to construct the pharmaceutically important 3-benzyl-3-alkyloxindole scaffold in moderate to good yields. Copyright