1638238-46-6

Basic information

• Product Name: 2-pentyl-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine
• Synonyms: 2-pentyl-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine
• CAS NO: 1638238-46-6
• Molecular Weight: 395.566
• Mol File: 1638238-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-pentyl-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-pentyl-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine(1638238-46-6)
• EPA Substance Registry System: 2-pentyl-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine(1638238-46-6)

Safety Data

• Hazardous Substances Data: 1638238-46-6(Hazardous Substances Data)

Upstream product

• 884866-01-7 1-(4-methylbenzensulfonyl)-4-phenyl-1H-1,2,3-triazole 
• 77192-27-9 (E)-1,3-nonadiene 

Relevant articles and documents

The divergent synthesis of nitrogen heterocycles by rhodium(II)-catalyzed cycloadditions of 1-sulfonyl 1,2,3-triazoles with 1,3-dienes

The first rhodium(II)-catalyzed aza-[4+3] cycloadditions of 1-sulfonyl 1,2,3-triazoles with 1,3-dienes have been developed, and enable the efficient synthesis of highly functionalized 2,5-dihydroazepines from readily available precursors. In some cases, the reaction pathway could divert to formal aza-[3+2] cycloadditions, thus leading to 2,3-dihydropyrroles. In this context, the titled reaction represents a capable tool for the divergent synthesis of two types of synthetically valuable aza-heterocycles from common rhodium(II) iminocarbene intermediates. On the (di)verge: Rhodium(II)-catalyzed cycloadditions of 1-sulfonyl 1,2,3-triazoles with 1,3-dienes have been developed and enable the efficient and divergent synthesis of two types of synthetically valuable nitrogen heterocycles, 2,5-dihydroazepines and 2,3-dihydropyrroles, by formal [4+3] and [3+2] cycloadditions, respectively. Ts=4-toluenesulfonyl.